Efficacy of Physical Therapy for Knee Pain
Analysis from Dr. Mark Thomas Rathjen PT, DPT, CSCS

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In the article below, you will see a very detailed analysis and systematic review of treatment of knee pain. This specifically is in relationship to the patella femoral component of knee pain.
The knee cap has a role of increasing the level arm of the quads to increase the strength of the extensor group. It slides between the condyles of the femur much like a train on its tracks. If it becomes pulled to a side there is some increased tension and friction that will manifest itself as knee pain in the patellar tendon. As stated below, and much studied in the clinical model, it’s a fallacy to only focus on the knee and muscle surrounding such.
The hip is a major component of stability, associated mechanical strain and control. I would argue it’s the most important component of knee health and often is the sole instigator in knee pain. If there is a force the hip cannot control, absorb or stabilize, the knee will bear the brunt of the force. Also important is the side opposite of the injury, as our bodies tend to counter balance and compensate in that manner. If the right knee patellar tendon is becoming irritated during squatting, it could also be an issue with the left side as a compensatory mechanism.
A full lower extremity analysis is vital to find the root of the issue and tackle it head on. Consequently, that’s what we are for. A trained Doctor of Physical Therapy can find the mechanical issues, asymmetries, weaknesses and functional compensation patterns responsible for your pain and injury. Make sure your provider is training in sports rehab and conditioning of athletes  This is the most efficient way to resolve symptoms and prevent them for the future.
A knee is a terrible thing to waste…
Published online 2015 Jul 22. doi: 10.1589/jpts.27.2387
PMCID: PMC4540887
PMID: 26311988

Effectiveness of therapeutic physical exercise in the treatment of patellofemoral pain syndrome: a systematic review

Pablo Alba-Martín,1 T Gallego-Izquierdo,1 Gustavo Plaza-Manzano,2 Natalia Romero-Franco,3 Susana Núñez-Nagy,1and Daniel Pecos-Martín1,*
Author information Article notes Copyright and License information Disclaimer

INTRODUCTION

Patellofemoral pain syndrome (PFPS) is a structural disorder of the patellofemoral joint whose main characteristics are peripatellar, anterior, and even retropatellar pain that increases with knee flexion and extension (i.e., actions such as running, going up and down stairs, walking, and squatting and postures such as prolonged sitting or sitting on the knees), ). Joint crepitus in flexion movements and instability in loading actions are also frequent).

The factors that contribute to PFPS are unclear. Many authors have suggested risk factors, including weak extensor musculature primarily in the vastus medialis), a high body mass index), misalignment of the lower limbs, and excessive foot pronation that internally rotates the tibia and increases knee valgus); however, some scientific evidence suggests that these are not risk factors,,).

Because PFPS is a non-degenerative pathology, conservative management often results in complete recovery, particularly in young patients). However, the appropriate clinical approach to this syndrome remains unclear due to the variety of treatments that have been applied and the studies that have analyzed the pathology of PFPS. Although some reviews addressing PFPS have been conducted, no author has yet reviewed all physical exercise methods for patients with PFPS,,,). Thus, this study aims to perform a systematic review to determine whether conservative treatments that employ physical exercise improve the pain and function of patients with patellofemoral pain syndrome.

SUBJECTS AND METHODS

Clinical trials related to PFPS were considered if they included physical exercise as a conservative management and included instruments that measured pain, such as pain scales, and function. No year limitations were included to avoid the exclusion of relevant results, and English, Spanish, French, and Portuguese were the languages considered. Studies were excluded if the analyzed population included individuals suffering from associated diseases or included surgery or management approaches involving nonphysical methods.

In the computer-based search, PubMed, Cochrane Library, Physiotherapy Evidence Database (PEDro), and the University Library of the city database were considered. The following keywords were used: “patellofemoral pain syndrome” [MeSH], “physical therapeutic modalities” [MeSH], “physical therapy” [MeSH], and “physical exercise” [MeSH].

The Critical Appraisal Skills Program in Spanish (CASPe)) was the scale employed to measure the methodological qualities and validities of the selected articles (Table 1). Three investigators independently evaluated every article.

Table 1.

Methodological quality of studies using the CASPe scale (Critical Appraisal Skills Program in Spanish)
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RESULTS

The search strategy initially produced 90 articles. After analysis, ten studies were considered to have met the inclusion criteria. Table 1 shows the quality evaluations of the selected articles with the CASPe scale. There was agreement in the scoring of all studies between the three investigators who evaluated the studies according the CASPe scale. The highest CASPe score was 10/10, and the average was 8.5.

The ten studies involved 420 subjects, with age most frequently ranging between 18–35 years (Table 2).

Table 2.

Main aspects of the studies included
Authors (sample size: gender; age) Characteristics of sample Variables Results
Herrington et al. (n=45: male; 18–35 years) 6 wk: SJNWBE (n=15) vs MJWBE (n=15) vs any exercise (n=15) KES, VAS, MKS All patients improved knee pain, function, extension strength.
Syme et al. (n=69: gender and age not specified) 8 wk: vastus medialis selective exercises (n=23) vs quad general exercises (n=23) vs any exercise (n=23) MPQ, MFIQ, SF-36, PGI Both intervention groups similarly reduced pain and improved knee function.
Dolak et al. (n=26: female; 16–35 years) 4 wk: hip external rotators and abductors muscle exercises (n=17) vs quad exercises (n=16) VAS, LEFS, HABD, HER, KES Hip exercises resulted in pain relief and higher hip muscles strength after the first 4 weeks. At 8 weeks, both groups showedimprovemalet.
Fukuda et al. (n=64: gender not specified; 18–32 years) 4 wk: knee muscles exercises (n=20) vs knee muscle + hip muscles exercises (n=21) vs any exercise (n=23) NPRS, LEFS, AKPS, SLSHT Both intervention groups showed similar improvemalets in pain and function.
Avraham et al. (n=30: gender not specified; 35 years average) 3 wk: quad exercises + TENS (n=10) vs hip external rotators and abductors exercises + TENS (n=10) vs knee and hip exercises + TENS (n=10) VAS, PFJES Both intervention groups had pain and function improvemalets, but group 3 had significantly higher improvemalets.
Khamyambasi et al. (n=28: female; 29 years average) 8 wk: hip muscles exercises (n=14) vs placebo treatmalet (n=14) VAS, WOMAC, HS; at 8 wk and 6 months Hip exercises resulted in less pain and higher health status in short and long terms.
Khamyambasi et al. (n=36: male and female; 28 years average) 8 wk: hip posterolateral exercises (n=18) vs quadriceps exercises (n=18) VAS, WOMAC; at 8 wk and 6 months Hip exercises resulted in less pain and higher health status in short and long terms.
Nakagawa et al. (n=14: male and female; 17–40 years) 6 wk: quadriceps exercises and hip external rotators and abductors exercises (n=14) vs quadriceps exercises (n=14) VAS, EIKEPT, HAHLREPT, EMG of gluteal medialis Hip+quad exercises resulted in less pain and an increase in electromyographic activity in the gluteal medialis.
Moyano et al. (n=74: gender not specified; 40.2 ± 3.29 years) 16 wk: classic stretching (n=35) vs PNF stretching (n=33) vs educational intervention (n=26) AKPS, VAS, Q-angle, thigh perimeter, knee ROM PNF and aerobic exercise improved function, pain, and ROM after 16 weeks and had better results than classic stretching
Lee J et al. (n=34: male and female; 22.8 ± 3.4 years) 8wk: elastic band exercises (n=11) vs sling exercises (n=13) vs control group (n=10) Dynamic Q-angle, VAS, onset time VL, onset time VMO Both intervention groups improved pain relief, Q-angle, and onset time.

VAS: Visual Analogue Scale; SJNWBE: Single joint quadriceps exercise; MJWBE: multiple-joint quadriceps exercise; TENS: Transcutaneous Electrical Nerve Stimulation; KES: Knee Extension Strength; KPS: Kujala Patellofemoral Score; ISM: Isometric Strength Measurement; FIQ: Functional Index Questionnaire; HAHLREPT: Hip Abductor and Hip Lateral Rotators Eccentric Peak Torque; EIKEPT: Eccentric Isokinetic Knee Extensor Peak Torque; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index; HS: Health Status; PFJES: Patello-femoral Joint Evaluation Scale; NPRS: Numeric Pain Rating Scale; LEFS: Lower Extremity Function Scale; AKPS: Anterior Knee Pain Score; SLSHT: Single-limb Single Hop Test; HABD: hip abductors; HER: hip external rotators; MKS: Modified Kujala Questionnaire; MPQ: McGill Pain Questionnaire; MFIQ: Modified Functional Index Questionnaire; PGI: Patient Generated Index; SF-36: Short form-36 Health Survey; ROM: range of motion; VL: vastus lateralis; VMO: vastus medialis oblique; FPPA: frontal plane proyection angle of the knee; EMG: electromiography

The pain assessment tools included the VAS (Visual Analogical Scale) in the majority of studies, the NPRS (Numeric Pain Rating Scale), AKPS (Anterior Knee Pain Scale), and MPQ (McGill Pain Questionnaire) were also employed (Table 2). The function assessment tools included a high variety of scales that involved general health status (HS, Health Status; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index; FIQ, Functional Index Questionnaire; SF36, Short form-36 Health Survey) and local knee function (KES, Knee Extension Strength; LEFS, Lower Extremity Function Scale; ISM, Isometric Strength Measurement; PFJES, Patello-femoral Joint Evaluation Scale).

Regarding the intervention, two studies employed exercises for the knee extensor muscles; seven studies included exercises for the external rotators and hip abductor muscles; and one study considered stretching exercises in addition to physical exercise (Table 2). Studies of interventions that included knee extensor exercises reported reduced pain and improved knee function due to an increase in the extension force and range of motion of the knee in PFPS patients. Studies that included exercises for the hip external rotators and abductor muscles reported that the combination of hip external rotator, abductor, and quad strengthening reported lower values for pain level and function earlier than quad strengthening alone. The study that included stretching exercises revealed improvements in pain, function, and the range of motion of the knee, but these results were observed when the stretching protocol included PNF (proprioceptive neuromuscular facilitation) techniques (Table 2).

DISCUSSION

The main finding of the present systematic review is that physical therapy protocols based on strengthening exercises of the hip external rotators and the abductor muscles results in greater pain relief among PFPS patients than those based only on strengthening exercises for the quadriceps, ). Stretching exercises for the muscles of the knee and hip also improved the function, pain and range of motion of PFPS patients, and PNF was the most appropriate type of stretching exercise to add to active exercise.

Previously, quadriceps strengthening has been reported to exert pain, and function benefits in PFPS, , , ) because patellar misalignment may be induced by a greater force from the vastus medialis, ). However, a study by Syme et al.) showed that specific exercises for the vastus medialis resulted in the same level of pain relief as general exercises for the quadriceps muscle). Supporting these results, Cowan et al.) reported a nonsignificant difference between activations of the vastus medialis and vastus lateralis, which is suggestive of the difficulty of selectively activating the vastus medialis muscle).

Also, authors have stated that the isolated performance of quadriceps exercises during the initial phase of PFPS rehabilitation might irritate the patellofemoral structures due to the effects of the high levels of pressure and force during the exercises on weak knee extensor musculature). Therefore, many authors have recently added exercises for the external rotators and abductor muscles to PFPS treatment protocols, , ,,,) due to the biomechanical influences of these muscles on femur alignment: a lack of motor control from the hip external rotators and abductor muscles would increase femur rotation under the patella while standing. Additionally, the performance of quadriceps strengthening exercises with a weak extensor musculature increases the pressure and force on the patellofemoral structures). Nakagawa et al.) and Fukuda et al.) reported greater pain relief when patients performed a combination of exercises for the hip external rotators, abductor, and quadriceps muscles compared with quadriceps exercises alone, ). Nakagawa also reported greater electromyographic activation of the gluteus medialis, which is directly related to pain relief and functional improvements). This finding might explain the pain relief that was experienced by patients while walking down stairs) (a situation in which the hip muscles are needed for motor control, )) in the study by Fukuda et al). Similarly, Dolak et al.) reported earlier pain relief when participants performed 4 weeks of exercises for the external rotators and abductor muscles compared with exercises for the quadriceps muscle; both of these programs were performed prior to 4 weeks of functional rehabilitation). Moreover, Khayambashi et al. reported that the performance of isolated hip strengthening reduced pain intensity and improved health status compared with a placebo intervention). Later, Khayambashi et al., ); demonstrated that hip posterolateral exercises produced greater pain relief and a better health status than quadriceps exercises did, and these improvements were maintained after 6 months, ).

In addition, stretching of knee and hip muscles might help improve pain, function, and range of motion in PFPS patients. However, among the stretching exercises, the PNF type seems to be more effective than classic stretching in terms of pain relief, functional improvements, and knee range of motion).

Although many authors have examined the influences of the hip external rotator and abductor muscles on PFPS management,,,,,), the etiology of this syndrome remains unclear. Future research is needed to identify the etiologic mechanism and create more adequate treatments. Also, the high variety of methods to assess pain used by the authors of the studies included in this review hampers comparison of their results. While the majority of the studies used the Visual Analog Scale as the instrument to determine pain levels, the McGill Pain Questionnaire and Anterior Knee Pain Scale were also frequently employed to assess pain. Regarding function, the variety is higher, which makes the comparison of results very difficult.

The most effective patellofemoral pain syndrome management initially includes strengthening exercises for the hip external rotator and abductor muscles due to their roles in knee biomechanics. The addition of exercises for the extensor muscles and proprioceptive neuromuscular facilitation stretching improves the pain relief in PFPS.

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